Impact of directly observed treatment on tuberculosis

Watch video Geneva —Tuberculosis, or TB, continues to be the leading cause of death from a single infectious agent worldwide, according to the Global TB Report Every day, there are 28, new TB cases and 4, related deaths. It is estimated that public health systems miss approximately 40 per cent of the new TB cases. Social determinants of health such as poor nutrition status, poor living and working conditions, low education and awareness and low access to health care contribute to the potential of contracting TB.

Impact of directly observed treatment on tuberculosis

This article has been cited by other articles in PMC. Introduction Tuberculosis TB control has been accorded a high priority within the health sector as it is a major public health problem.

The programme uses sputum negativity and weight gain as prognostic indicators but does not consider any other dimension of health. It has been seen that apart from physical symptoms, TB patients face various problems that are social and economic in nature.

The effect of disease on each dimension can be assessed using instruments, which are either generic or specific. The impact of various chronic diseases like hypertension, leprosy and asthma and depression has been studied using these instruments. It is required to incorporate the measurement of QoL of TB patients to have an in-depth understanding of the effect of disease on various dimensions of health.

This would enable the health care professionals and the system to devise relevant interventions to improve the quality of the programme.

Patients who had known respiratory co-morbidity other than TB or any known and diagnosed chronic illness, which may affect QoL, were excluded from the study.

Controls were selected from general population of areas catered to by the DOT centres after matching for age, gender and socio-economic status. A total of 90 cases who met the inclusion criteria were interviewed at the study centre itself within first three days of registration using a pre-designed, pre-tested questionnaire regarding socio-demographic data, perception about his QoL using WHO QoL BREF Hindi version which is a item scale designed by WHO.

It has four domains viz: For comparison between mean scores of groups, independent t-test was used. The mean scores for different domains were used in the analysis.

The overall QoL was assessed using specific questions and the mean scores for it were not the average of the mean scores of the domains. Results Out of total 90 patients with TB who were included in the study, 51 The mean per capita income per month of the study subjects was Rs. The TB patients had significantly lower mean scores than the controls for overall QoL and its domains.

The most affected domains were physical and psychological. The patients scored highest in the Social domain The mean difference in scores for the cases and the controls was highly significant for all the domains and the overall QoL; physical mean diff.

Table 1 Mean quality of life scores by domains of quality of life Domain.*QVAR MDI=QVAR Inhalation Aerosol. Other adverse reactions that occurred in clinical trials using QVAR REDIHALER with an incidence of 1% to 3% and which occurred at a greater incidence than placebo were back pain, headache, pain, nausea and cough.

Impact of directly observed treatment on tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB). Tuberculosis generally affects the lungs, but can also affect other parts of the body.

Most infections do not have symptoms, in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those. Tuberculosis of spine or TB spine or spinal TB was first described by Percivall Pott.

He noted this as a painful kyphotic deformity of the spine associated with then condition is also referred to as Pott’s disease or Pott’s spine.

Tuberculosis (TB) is a socioeconomic disease.

Impact of directly observed treatment on tuberculosis

To state that Mycobacterium tuberculosis is the cause of TB would be an over-simplification of reality. Seldom has The politics, economics and impact of directly observed treatment (DOT) in India ZF Udwadia and LM Pinto Department of Pulmonology, P.D.

Hinduja National Hospital and Medical. The Revised National Tuberculosis Control Programme (RNTCP), based on the Directly Observed Treatment Short course (DOTS) strategy, was launched in in India.

The question of what DOTS has or has not accomplished over the past 15 years is a central technical question. The problems of drug resistant TB, HIV co-infection, and the social costs of TB in India are staggering.

With an estimated annual incidence of 99, cases of MDR–TB (1), the highest in the world, drug resistant TB is a serious threat to control of TB in India.

Directly observed treatment, short-course - Wikipedia